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enquirebio 929-MSM5-P0说明书

 更新时间:2020-04-28 点击量:556

enquirebio 929-MSM5-P0说明书

CD14 (Monocyte / Macrophage Marker) Ultraspecific Antibody

Tested against >20,000 Human Proteins

Product NumberDescriptionPrice
929-MSM5-P0Size: 20 ug, Tag: Unconjugated$ 228.00
929-MSM5-P1Size: 100 ug, Tag: Unconjugated$ 488.00
929-MSM5-P1ABXSize: 100 ug, Tag: Unconjugated$ 488.00

SDS-PAGE Analysis Purified CD14 Mouse Monoclonal Antibody (LPSR/2385). Confirmation of Integrity and Purity of Antibody.

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SDS-PAGE Analysis Purified CD14 Mouse Monoclonal Antibody (LPSR/2385). Confirmation of Integrity and Purity of Antibody.Analysis of Protein Array containing more than 19,000 full-length human proteins using CD14 Mouse Monoclonal Antibody (LPSR/2385) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target.  A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.Formalin-fixed, paraffin-embedded human Tonsil stained with CD14 Mouse Monoclonal Antibody (LPSR/2385).

 

人类抗CD14(单核细胞/巨噬细胞标记)抗体产品属性

物种:人类

经过测试的应用程序: IHC。

克隆性:单克隆

抗CD14(单核细胞/巨噬细胞标记)抗体克隆: LPSR / 2385

克隆LPSR / 2385宿主和同种型:小鼠IgG1,κ

抗人类CD14(单核细胞/巨噬细胞标记)阳性对照样品: THP-1细胞和人类单核细胞。淋巴结和扁桃体。

抗体LPSR / 2385染色的细胞定位:细胞表面

缓冲液和稳定剂: 10mM PBS,含0.05%BSA和0.05%叠氮化物。也可不带BSA和叠氮化物。

抗体浓度: 200 ug / ml

抗体纯化方法:从生物反应器浓缩物中纯化的蛋白A / G。

免疫原:人CD14蛋白的重组片段(约aa 25-148)(请致电以获取更多信息。)

储存条件:储存于2至8 C(冷藏)。正确存放后可稳定保存24个月。

CD14(单核细胞/巨噬细胞标记)以前观察到的抗体染色模式

限制与保证

inquire Bio的产品CD14(单核细胞/巨噬细胞标记)MonoSpecific抗体仅可用于研究用途(仅限RUO)。正确存放后,保证该抗体可工作两年。

CD14(单核细胞/巨噬细胞标记)一般信息 备用名 脂多糖受体;LPS-R;LPSR;Mo2; 单核细胞分化抗原14; 骨髓细胞特异性富亮氨酸糖蛋白 分子量 55kDa的 染色体位置 在蓝色冰上的船。 精选数据库和生物信息学数据 基因符号 929 Entrez基因ID CD14 UniProt ID P08571 UniGene ID Hs163867 COSMIC ID链接 CD14 KEGG基因ID 卫生署:929 CD14(单核细胞/巨噬细胞标记)的概述。 识别55kDa的蛋白质,称为CD14(也称为脂多糖受体)。CD14在单核细胞和巨噬细胞上强烈表达,在嗜中性粒细胞表面弱表达。CD14通过与糖基磷脂酰肌醇(GPI)相连而锚定在细胞上,并充当LPS和LPS结合蛋白(LBP)的复合物的高亲和力受体。可溶性CD14也与LPS结合,在生理浓度下作为LPS激动剂起作用,并且在较高浓度下具有细胞活化中的LPS拮抗作用。