Dianova公司为德国的病理免疫组化产品供应商，具备先进的抗体制备工艺及严格的质控系统，产品在上享有良好的声誉。
Dianova DIA-AX1说明书
Art.-Nr.
DIA-AX1
特异性
ATRX
物种反应性
人的
寄主物种
老鼠
同型
的IgG1 / K
克隆
AX1
克隆性（单克隆/多克隆）
单克隆
应用
免疫组化（石蜡包埋切片）
免疫组化（IHC）
共轭
非结合
稀释
组织 - /细胞化学1：100-1：200
格式
纯化的冻干抗体（来自培养上清液）
产品系列/主题
肿瘤标志物/生物学
神经生物学
免疫组织化学
有可能的使用
仅供研究使用
温度 - 储存
2-8℃
搜索代码
FFPE
石蜡
DIAAX1
制造商/品牌
dianova
标准福尔马林固定石蜡包埋胶质瘤切片中人ATRX的免疫组织化学。
A：抗ATRX抗体克隆AX1在1p / 19q共同缺失的神经胶质瘤中的强核反应。
B：通过抗ATRX免疫组织化学记录的具有完整染色体1p / 19q的神经胶质瘤中核ATRX蛋白表达的丧失。
（A）1p / 19q的ATRX染色缺失胶质瘤
B）神经胶质瘤中ATRX丢失，完整1p / 19q
（图片由德国汉堡UKE神经病理学系Marcus Glatzel教授提供）
ATRX（dianova clone AX1）和IDH1R132H（dianova clone H09）的组合免疫组织化学
取代了分子检测。
用于诊断星形细胞瘤和少突神经胶质瘤的常规实用方法开始于针对ATRX和IDH1 R132H表达的执行IHC。用ATRX和IDH1 R132H的初始IHC逐步分析分子参数，然后进行1p / 19q分析，然后通过IDH测序，显着减少了明确诊断所需的分子检测次数（Reuss等，2015）。
背景
ATRX突变，IDH1突变和染色体1p / 19q共缺失是弥漫性胶质瘤亚型诊断的关键分子因素。胶质瘤中的ATRX突变导致核ATRX表达的丧失，其可通过IHC分析诊断。ATRX表达的丧失接近于与IDH1突变肿瘤中的1p / 19q共缺失相互排斥。因此，可以进行ATRX免疫组织化学以通过FISH技术取代1p / 19q状态的费力分析。
参考
Dianova2019年产品价格表
货号 | 品名 | 规格 | 价格 | 品牌 |
DIA-100 | Anti-Fibroblasten (CD90) (Hu) from Mouse (Clone: AS02) | 200µg | 4680 | dianova |
DIA-100-M | Anti-Fibroblasten (CD90) (Hu) from Mouse (Clone: AS02) | 20µg | 0 | dianova |
DIA-120 | Anti-Fibroblasten (CD90) (Hu) from Mouse (Clone: AS02) -FITC | 100test | 5360 | dianova |
DIA-530-P05 | Anti-p53 (Hu) from Mouse (Clone: CC53) | 0.5ml | 4780 | dianova |
DIA-530-M | Anti-p53 (Hu) from Mouse (Clone: CC53) | 0.1ml | 0 | dianova |
DIA-670-P05 | Anti-Ki-67/MIB1 (Hu) from Mouse (Clone: Ki-67P) CE-IVD | 0.5ml | 4780 | dianova |
DIA-670-P1 | Anti-Ki-67/MIB1 (Hu) from Mouse (Clone: Ki-67P) CE-IVD | 1ml | 6500 | dianova |
DIA-670-M | Anti-Ki-67/MIB1 (Hu) from Mouse (Clone: Ki-67P) CE-IVD | 0.1ml | 0 | dianova |
DIA-700-P05 | Anti-GFAP (Hu) from Mouse (Clone: IF3) CE-IVD | 0.5ml | 4780 | dianova |
DIA-700-M | Anti-GFAP (Hu) from Mouse (Clone: IF3) CE-IVD | 0.5ml | 0 | dianova |
DIA-AX1 | Anti-ATRX (Hu) from Mouse (Clone: AX1) | 0.5ml | 6760 | dianova |
DIA-CAL-100 | Anti-CALRETICULIN mutation (Hu) from Mouse (Clone CAL2) | 0.1ml | 5960 | dianova |
DIA-CAL-250 | Anti-CALRETICULIN mutation (Hu) from Mouse (Clone CAL2) | 0.25ml | 13960 | dianova |
DIA-H09 | Anti-IDH1 R132H (Hu) from Mouse (Clone: H09) CE-IVD | 0.5ml | 9640 | dianova |
DIA-H09-M | Anti-IDH1 R132H (Hu) from Mouse (Clone: H09) CE-IVD | 0.1ml | 2840 | dianova |
DIA-H09-L | Anti-IDH1 R132H (Hu) from Mouse (Clone: H09), prediluted, ready-to-use | 8ml | 9640 | dianova |
DIA-W09 | Anti-IDH1 (Hu) from Rat (Clone: W09) | 0.5ml | 4960 | dianova |
DIA-TG1 | Anti-TIGIT (Hu) from Mouse (Clone TG1) | 0.5ml | 20400 | dianova |
DIA-TG1-M | Anti-TIGIT (Hu) from Mouse (Clone TG1) | 0.1ml | 5720 | dianova |
DIA-TC8 | Anti-CD8 (Hu) from Mouse (Clone TC8 ) | 0.5ml | 9200 | dianova |
DIA-P16-OD | Anti-P16 (Hu) from Mouse (Clone JAP16) | 0.1ml | 7360 | dianova |
DIA-303 | Anti-CD3 (Ms, FFPE) from Rat (Clone: HH3E) | 0.5ml | 6900 | dianova |
DIA-310 | Anti-CD31 (Ms, FFPE) from Rat (Clone: SZ31) | 0.5ml | 8040 | dianova |
DIA-404 | Anti-CD4 (Ms, FFPE) from Rat (Clone GHH8) | 0.2ml | 6900 | dianova |
DIA-808 | Anti-CD8a (Ms, FFPE) from Rat (Clone GHH8) | 0.2ml | 6900 | dianova |
DIA-60 | Anti-FasL, soluble (Hu) from Mouse (Clone: 94) | 1ml | 4760 | dianova |
DIA-900-100 | Anti-HIS-Tag (affinity 3x 10‐10M (Biacore™) from Mouse (Clone: 13/45/31) | 100µg | 2960 | dianova |
DIA-900-200 | Anti-HIS Epitope-Tag (affinity 3x 10‐10M (Biacore™) from Mouse (Clone: 13/45/31) | 200µg | 5160 | dianova |
DIA-900-FITC | Anti-HIS Epitope-Tag (affinity 3x 10‐10M (Biacore™) from Mouse (Clone:13/45/31) -FITC | 1ml | 5960 | dianova |
DIA-900-BIOT | Anti-HIS Epitope-Tag (affinity 3x 10‐10M (Biacore™) from Mouse (Clone:13/45/31) -Biotin | 100µg | 3960 | dianova |
DIA-910-200-ABF | Anti-HIS Epitope-Tag (affinity 3x 10‐10M (Biacore™) from Mouse (Clone:13/45/31) Acid/BSA-free | 200µg | 4960 | dianova |
DIA.910-1MG-ABF | Anti-HIS Epitope-Tag (affinity 3x 10‐10M (Biacore™) from Mouse (Clone:13/45/31) Acid/BSA-free | 1mg | 19840 | dianova |
SCR-028841 | IS Adhesion Slides | 50pcs. | 1620 | dianova |
SCR-028855 | IS Adhesion Slides | 5pcs. | 询价 | dianova |
SCR-028842 | IS Adhesion Slides | 100pcs. | 2440 | dianova |
SCR-038447 | Immunoselect Antifading Mounting Medium | 15ml | 960 | dianova |
SCR-038587 | Immunoselect Antifading Mounting Medium | 1ml | 询价 | dianova |
SCR-038448 | Immunoselect Antifading Mounting Medium DAPI | 15ml | 1180 | dianova |
SCR-038588 | Immunoselect Antifading Mounting Medium DAPI | 1ml | 询价 | dianova |
SCR-038449 | Immunoselect Antifading Mounting Medium PI | 15ml | 1180 | dianova |
SCR-072967 | Immunoselect Mounting Medium without hardener | 15ml | 960 | dianova |
SCR-093035 | Immunoselect Antifading Mounting Medium DAPI without hardener | 15ml | 1180 | dianova |
SCR-093036 | Immunoselect Antifading Mounting Medium PI without hardener | 15ml | 1180 | dianova |
DIA-0302-I | p53-auto antibody ELISA-Kit (Human) CE-IVD | 96test | 10960 | dianova |
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