世界*实验材料供应商Genisphere 正式授权上海起发为其中国代理,Genisphere 在一直是行业的*,一直为广大科研客户提供zui为优质的产品和服务,上海起发一直秉承为中国科研客户带来的产品,的服务,签约Genisphere 就是为了给广大科研客户带来更加完善的产品和服务,您的满意将是我们zui大的收获
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Genisphere公司专注于核酸标记技术的发明和新产品的开发。该公司推出的3DNA Dendrimer技术是对核酸标记技术的重大创新,具有广阔的发展前景。3DNA Dendrimer技术:3DNA Dendrimer是由多个交错的自然或合成的3DNA单体结构单位组成的复杂的分枝状分子构型。每个3DNA单体由两条中央部分互补的DNA链组成,退火时两条链会形成一个中间双链两头单链的结构。3DNA单体之间的单链通过碱基互补组成了3DNA Dendrimer构型。3DNA Dendrimer的单链是标记物的结合位点。特点:灵活的标记:3DNA Dendrimer可以结合多种标记物,可以满足多种检测的需要
信号增强作用:每个3DNA Dendrimer分子平均可以结合200分子的标记物,因此杂交时信号增强了200倍以上
In 1986, the first patent applications covering the design and use of 3DNA technologywere filed. Determined to build a strong portfolio and reward our scientists, we have worked hard to grow the list of patents. Genisphere was incorporated in 1997 and proudly launched its first 3DNA Expression Array Detection kit, developed in conjunction with Harvard-affiliated researchers, in 1999.
In 2006, Genisphere was honored to receive a Frost & Sullivan Technology Innovation Award for this product line. With an established business in microarrays, Genisphere turned to RNA amplification technology, offering a new method with a twist—the ability to amplify mRNA in the sense orientation. Product launches included SenseAMP in 2004, RampUP in 2006, and Sensation in 2011. All had a particular focus on clinical FFPE samples. In 2008, Genisphere’s RNA amplification technology was incorporated into the Pathwork Diagnostics Tissue of Origin Test, which was cleared by the FDA in 2010. The Sensation technology was licensed to Affymetrix in 2011 for microarray applications. Genisphere launched the world’s first microRNA labeling kit in 2005. The release of FlashTag in 2007 enabled customers to scale up their microRNA research, offering a single-tube labeling reaction with no purification required. Genisphere’s microRNA labeling technology has been incorporated into microarray products from Invitrogen (2006, 2008) and Luminex products from Marligen (2008). Additional co-marketing (2009) and OEM (2011) structures with Affymetrix validate the power of FlashTag. Single-tube UltraAmp reagents were first launched in 2005, with new varieties added in 2008. Now almost all UltraAmp signal amplifiers are custom made, once again proving the importance of collaboration. Genisphere found particular success in providing custom reagents to improve the limit of detection in lateral flow point-of-care diagnostic tests and licensed 3DNA technology to BBI Solutions for lateral flow assay development for enhanced performance and sensitivity (2014).
In 2009, Genisphere LLC was formed, inheriting all of the legacy technology and inlectual property from its predecessor, Genisphere, Inc. With established success of the 3DNA technology in life science and diagnostic applications, the company turned its focus to targeted drug delivery. Since research has shown DNA to be a non-toxic, biocompatible material in vivo, Genisphere aimed to become a commercial source of highly targeted DNA-based nanocarriers. Genisphere's first task was to re-engineer its DNA strands based on three goals for the final 3DNA construct.
After meeting these objectives, Genisphere expanded its efforts in cellular targeting. Leveraging its experience in antibody-DNA conjugation, the company studied attachment of 3DNA to antibody fragments, peptides, sugars, vitamins and other targeting devices for specific cellular delivery. After producing these data, Genisphere established several key collaborations to generate preclinical data showing the versatility and efficacy of the 3DNA platform in targeted delivery of small drugs, biologics and nucleic acids. To date, the 3DNA platform has proven to provide cell-specific (cytosolic and nuclear) delivery of drugs with functional intracellular effects without apparent toxicity. The flexibility of the 3DNA platform to deliver hundreds of tracking labels to targeted tissues provides an option to incorporate a companion diagnostic into the drug development process. Genisphere continues to seek partnerships with biotechnology and pharmaceutical companies. The company is also advancing its own lead oncology compounds based on the 3DNA drug delivery platform.
公司:www.genisphere.com/
我们公司zui大优势是强大的采购,
1:基本什么都能进口,血清,抗体,耗材,还有部分限制进口的,
2:货品全,现经营过700多个品牌,基本所有生物试剂耗材都可以进口,特别是冷偏的产品那就更有优势,
3:提供加急服务,一般1-2周到货,超过时限加急费全免
4:价格公道,绝大部分价格有优势,当然不能保证100%产品都是,因为意味着没有服务.
5:良好的信誉,大部分客户我们提供货到付款服务,客户包括清华,北大 交大 复旦,中山等100多所大学,ROCHE,阿斯利康,国药 ,fisher等500多家公司
6:我们还是Santa,Advanced Biotechnologies Inc,Genisphere ,bangs,BBInternational,crystalchem,dianova,FD Neurotechnologies,Inc. FormuMax Scientific,Inc, GePromegaridege, Glycotope Biotechnology GmbH; iduron,Innovative Research of America, Ludger, neuroprobe,Genisphere , Polysciences,prospecbi, QA-BIO,quickzyme,FULLERLABS,INC,sterlitech;sysy,TriLink BioTechnologies,Inc;worthington-biochem,zyagen等几十家国外公司授权代理。
7:我们还是invitrogen,qiagen,Genisphere am,sigma;Promega,roche,merck, rnd,BD, GE,pierce,BioLegend等*批发,欢迎合作。
上海起发实验试剂有限公司
:杨建辉
400:
办公:
*8006
企业:
:http://www.qfbio.com/
地址:上海市浦东新区晨阳路225弄东方现代商业广场46号303室(近东亭路)