Spring Bioscience代理，spring bioscience丝氨酸/苏氨酸蛋白激酶B-RAF（BRAF）是Raf家族的一员。 BRAF突变在良性和恶性肿瘤是常见的。 BRAF改变和突变诱导激活段的构象变化中BRAF V600E突变占绝大多数，导致组成型激酶活性的BRAF的和下游目标连续的磷酸化。已在黑色素瘤，甲状腺乳头状癌，多形性xanthoastrocytomas，朗格汉斯细胞组织细胞增生症，卵巢交界性肿瘤，节细胞胶质瘤，结直肠癌，毛细胞型星形细胞瘤检测到BRAF V600E突变。
Spring Bio,Spring Bio代理,Spring Bioscience
| PRODUCT DETAILS: | |||
| TechnologyMouse Monoclonal | |||
| Clone NameVE1 | |||
| ApplicationIHC-P, WB | |||
| Species Reactivity | |||
| TestedHu | |||
| Predicted by homology | |||
| IsotypeMouse IgG2a | |||
| ImmunogenSynthetic peptide representing the BRAF V600E mutated amino acid sequence from amino acid 596 to 606 （GLATEKSRWSG） | |||
| Cellular LocalizationCytoplasm | |||
| Control TissueColon Carcinoma with BRAF V600E mutation | |||
| Regulatory RatingResearch Use Only （RUO） | |||
| Entrez673 | |||
| Storage Requirement2-8°C | |||
| Target Molecular Weight95 kDa | |||
| FormulationRefer to Data Sheet | |||
| Catalog No. | Volume | Dilution | |
| E19290 | 0.1ml | 50 | |
| E19292 | 0.5ml | 50 | |
| E19294 | 1.0ml | 50 | |
